1.1. Background: This study investigated the incidence of post-hepatectomy hypoalbuminemia and the necessity of intravenous albumin (ALB) supplement for hypoalbuminemia after laparoscopic hepatectomy (LH).
1.2. Methods: 980 patients with open hepatectomy (OH) and 198 patients with LH were matched on the propensity score by 2:1. The incidences of postoperative hypoalbuminemia and the usage of ALB injection on different postoperative days (POD) were compared. Preventive and risk factors of hypoalbuminemia were screened by logistic regression. Receiver operator characteristic (ROC) curve and nomogram were established to predict postoperative hypoalbuminemia.