1.1. Background and Aims: The role of histological scores in Ulcerative Colitis (UC) is debated. The primary endpoint was to assess, in a cohort of UC patients undergoing colonoscopy, the role of histological activity as a predictor of clinical activity at 1 year. Secondary endpoint was to assess the possible correlations between the degree of clinical, endoscopic and histological UC
activity as assessed by dedicated scores.